Endocrine Abstracts

Hyponatremia complicates 1% of hospital admissions and can be associated with serious CNS effects. We report a case of an 84-year-old woman with longstanding hyponatremia resulting in several hospital admissions because of acute confusion due to severe hypoatremia. This case emphasizes the need to consider selective vasopressin V2-receptor antagonist (Tolvaptan) as a potential therapy for hyponatremia secondary to the syndrome of inappropriate antidiuretic hormone (SIADH)....

Introduction: Hurler Syndrome, (MPS1H) is an inborn error of metabolism which was previously fatal in childhood. Bone marrow transplantation (BMT) has transformed the prognosis for these children. First BMTs are preconditioned with chemotherapy, and we have therefore put in place surveillance for endocrine sequelae. We present for the first time data on final adult height in children with MPS 1H post BMT, as well as the endocrine complications seen in this cohort.<p class=...